Ibrutinib, SNS-062, and CAR-NK for CLL (chronic lymphocytic leukemia)

Hi,

It’s been a bit crazy, but I wanted to share that I have posted on our nonprofit’s website http://cllsociety.org an interview from ASH about the particularities of ibrutinib as compared to other BTK inhibitors from the perspective of a Janssen executive, news about a new trial of an experimental BTK inhibitor that doesn’t bind to C481 and is therefore helpful to many who become resistant to ibrutinib due mutations in that binding site, and finally some promising information on CAR-NK cells, a possible step towards a scalable "off the shelf" cellular therapy.

It seems in CLL, every week brings news and that is a good thing. In contrast and to give some perspective, it has been more than a decade since there has been a new drug to treat MDS

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Stay strong.

We are all in this together.

Brian